Trial of ketoconazole in allergic bronchopulmonary aspergillosis.
نویسندگان
چکیده
منابع مشابه
[Allergic bronchopulmonary aspergillosis].
Allergic bronchopulmonary aspergillosis (ABPA) is a syndrome seen in patients with asthma and cystic fibrosis. It is characterized by chronic colonization of the airways with a ubiquitous fungus, Aspergillus fumigatus. The clinical expression of ABPA results from the complex interaction of chronic colonization of the airways with A fumigatus, host factors allowing this colonization, and the hos...
متن کاملAllergic bronchopulmonary aspergillosis.
There remains a lack of agreement on diagnostic criteria and approaches to treatment of patients with allergic bronchopulmonary aspergillosis (ABPA). The results of a survey of American Academy of Allergy, Asthma, & Immunology members regarding these 2 issues are presented and compared for concordance with published recommendations. The literature was reviewed for pertinent reports, and an elec...
متن کاملAllergic Bronchopulmonary Aspergillosis
Allergic bronchopulmonary aspergillosis (ABPA), a progressive fungal allergic lung disease, is a common complication of asthma or cystic fibrosis. Although ABPA has been recognized since the 1950s, recent research has underscored the importance of Th2 immune deviation and granulocyte activation in its pathogenesis. There is also strong evidence of widespread under-diagnosis due to the complexit...
متن کاملAllergic bronchopulmonary aspergillosis.
Allergic bronchopulmonary aspergillosis is an uncommon but serious respiratory condition characterized by chronic airway inflammation and airway damage resulting from persistent colonization by and sensitization to the fungus Aspergillus fumigatus. The immunopathogenesis of allergic bronchopulmonary aspergillosis involves several pathways. Aspergillus allergens stimulate an interleukin 5-mediat...
متن کاملA randomized trial of itraconazole in allergic bronchopulmonary aspergillosis.
BACKGROUND Allergic bronchopulmonary aspergillosis is a hypersensitivity disorder that can progress from an acute phase to chronic disease. The main treatment is systemic corticosteroids, but data from uncontrolled studies suggest that itraconazole, an orally administered antifungal agent, may be an effective adjunctive therapy. METHODS We conducted a randomized, double-blind trial of treatme...
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ژورنال
عنوان ژورنال: Thorax
سال: 1987
ISSN: 0040-6376
DOI: 10.1136/thx.42.10.831